This is the comedic debate of the 21st century. Which animated series is better? "Family Guy" or "The Simpsons"? Here are some comparisons broken down by characters:

First - Stewie vs Maggie

http://www.listafterlist.com/tabid/57/listid/7043//The+Two+Youngest+Maggie+Simpson+vs+Stewie+Griffin.aspx

Marge vs Lois

http://www.listafterlist.com/tabid/57/listid/7054/TV/The+Wives+Marge+Simpson+vs+Lois+Griffin.aspx

Meg vs Lisa

http://www.listafterlist.com/tabid/57/listid/7044/TV/The+Daughters+Meg+Griffin+vs+Lisa+Simpson.aspx

Brian vs Santa's Little Helper (etc.)

http://www.listafterlist.com/tabid/57/listid/7049/TV/Family+Guy+vs+The+Simpsons++The+Pets.aspx

Bart vs Chris

http://www.listafterlist.com/tabid/57/listid/7060//The+Sons+Bart+Simpson+vs+Chris+Griffin.aspx

and finally...
Peter vs Homer

http://www.listafterlist.com/tabid/57/listid/7070//Peter+Griffin+versus+Homer+Simpson.aspx